The Mustangs, 9-16, led 8-7 after the first quarter, trailed 21-12 at the half and 28-20 after three quarters.
Quincy Wicker led Northwest with 14 points. Cody Wicker added nine points. Cortlen Austin five points and nine rebounds and Truman Leicher pulled down eight rebounds.
Northwest collected 29 rebounds, 15 on the offensive glass.