Adella Randle El led the Lady Roadrunners with 15 points and a trey. Mia Wesley and Apiphany Woods added 11 points each.
Wesley and Woods each pulled down seven rebounds.
The Lady Roadrunners shot 33 percent for the game and made just one of 15 attempts from beyond the three-point arc.
Macy Wright led four Lady Raiders in double figures with 20 points.
Three Rivers led 38-24 at the half and led by as many as 20 points at 44-24 early in the second half.
The Lady Roadrunners fell to 17-6 on the season and are 7-5 in road games.